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To date, research on the effects of coffee enemas on glutathione levels is scarce

23 These symptoms can be severe in some patients, resulting in a pause of dose escalation, and if intolerable GI symptoms continue, a dose adjustment to the previous lower dose or a switch to an alternative GLP-1 RA should be considered

doi: 10.1016/j.intimp.2024.112262 173 CaoXLiLHuJZhuSSongSKongSet al